大阪大学免疫学フロンティア研究センター　免疫・生化学

Nakaya M., Tanaka M., Okabe Y., Hanayama R. and Nagata S.

Opposite effects of Rho family GTPases on engulfment of apoptotic cells by macrophages

J. Biol. Chem. 281, 8836-8842. (2006).

http://www.ncbi.nlm.nih.gov/pubmed/16439364?

Nagata S.

Apoptosis and autoimmune diseases

Iubmb Life 58, 358-362. (2006).

http://www.ncbi.nlm.nih.gov/pubmed/16754331?

Kawane K., Ohtani M., Miwa K., Kizawa T., Kanbara Y., Yoshioka Y., Yoshikawa H. and Nagata S.

Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages

Nature 443, 998-1002. (2006).

http://www.ncbi.nlm.nih.gov/pubmed/17066036?

Hanayama R., Miyasaka K., Nakaya M. and Nagata S.

MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure

Curr Dir Autoimmun 9, 162-72. (2006).

http://www.ncbi.nlm.nih.gov/pubmed/16394660?

Burgess B., Abrams T., Nagata S. and Hall M.

MFG-E8 in the retina and retinal pigment epithelium of rat and mouse

Mol. Vis. 12, 1437-1447. (2006).

http://www.ncbi.nlm.nih.gov/pubmed/17167398?

Bergsmedh A., Ehnfors J., Kawane K., Motoyama N., Nagata S. and Holmgren L.

DNase II and the Chk2 DNA damage pathway form a genetic barrier blocking replication of horizontally transferred DNA

Molecular Cancer Research 4, 187-195. (2006).

http://www.ncbi.nlm.nih.gov/pubmed/16547156?

Yoshida H., Okabe Y., Kawane K., Fukuyama H. and Nagata S.

Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

Nature Immunology 6, 49-56. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/15568025?

Yoshida H., Kawane K., Koike M., Mori Y., Uchiyama Y. and Nagata S.

Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells

Nature 437, 754-758. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/16193055?

Watanabe-Fukunaga R., Iida S., Shimizu Y., Nagata S. and Fukunaga R.

SEI family of nuclear factors regulates p53-dependent transcriptional activation

Genes Cells 10, 851-860. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/16098148?

Okabe Y., Kawane K., Akira S., Taniguchi T. and Nagata S.

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

J. Exp. Med. 202, 1333-1339. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/16301743?

Ohnishi H., Kaneko Y., Okazawa H., Miyashita M., Sato R., Hayashi A., Tada K., Nagata S., Takahashi M. and Matozaki T.

Differential localization of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 and CD47 and its molecular mechanisms in cultured hippocampal neurons

J. Neurosci. 25, 2702-2711. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/15758180?

Nagata S.

DNA degradation in development and programmed cell death

Annu. Rev. Immunol. 23, 853-875. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/15771588?

Iida S., Kohro T., Kodama T., Nagata S. and Fukunaga R.

Identification of CCR2, flotillin, and gp49B genes as new G-CSF targets during neutrophilic differentiation

J. Leukoc. Biol. 78, 481-490. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/15894583?

Hanayama R. and Nagata S.

Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8

Proc. Natl. Acad. Sci. U. S. A. 102, 16886-16891. (2005).

http://www.ncbi.nlm.nih.gov/pubmed/16275924?

Ueda T., Watanabe-Fukunaga R., Fukuyama H., Nagata S. and Fukunaga R.

Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

Mol. Cell. Biol. 24, 6539-6549. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15254222?

Shiraishi T., Suzuyama K., Okamoto H., Mineta T., Tabuchi K., Nakayama K., Shimizu Y., Tohma J., Ogihara T., Naba H., Mochizuki H. and Nagata S.

Increased cytotoxicity of soluble Fas ligand by fusing isoleucine zipper motif

Biochem. Biophys. Res. Commun. 322, 197-202. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15313191?

Nagata S.

Early work on the function of CD95, an interview with Shige Nagata

Cell Death Differ. 11, S23-S27. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15143352?

Miyazaki S., Ishikawa F., Fujikawa T., Nagata S. and Yamaguchi K.

Intraperitoneal injection of lipopolysaccharide induces dynamic migration of Gr-1(high) polymorphonuclear neutrophils in the murine abdominal cavity

Clin. Diagn. Lab. Immunol. 11, 452-457. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15138169?

Miyasaka K., Hanayama R., Tanaka M. and Nagata S.

Expression of milk fat globule epidermal growth factor 8 in immature dendritic cells for engulfment of apoptotic cells

Eur. J. Immunol. 34, 1414-1422. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15114675?

Kimura A., Naka T., Nagata S., Kawase I. and Kishimoto T.

SOCS-1 suppresses TNF-alpha-induced apoptosis through the regulation of Jak activation

Int. Immunol. 16, 991-999. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15173123?

Hanayama R., Tanaka M., Miyasaka K., Aozasa K., Koike M., Uchiyama Y. and Nagata S.

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

Science 304, 1147-1150. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15155946?

Hanayama R., Tanaka M., Miwa K. and Nagata S.

Expression of developmental endothelial locus-1 in a subset of macrophages for engulfment of apoptotic cells

J. Immunol. 172, 3876-3882. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15004195?

Asano K., Miwa M., Miwa K., Hanayama R., Nagase H., Nagata S. and Tanaka M.

Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice

J. Exp. Med. 200, 459-467. (2004).

http://www.ncbi.nlm.nih.gov/pubmed/15302904?

Tada K., Tanaka M., Hanayama R., Miwa K., Shinohara A., Iwamatsu A. and Nagata S.

Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1

J. Immunol. 171, 5718-5726. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/14634079?

Ogawa H., Ueda T., Aoyama T., Aronheim A., Nagata S. and Fukunaga R.

A SWI2/SNF2-type ATPase/helicase protein, mDomino, interacts with myeloid zinc finger protein 2A (MZF-2A) to regulate its transcriptional activity

Genes Cells 8, 325-339. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12653961?

Ogawa H., Murayama A., Nagata S. and Fukunaga R.

Regulation of myeloid zinc finger protein 2A transactivation activity through phosphorylation by mitogen-activated protein kinases

J. Biol. Chem. 278, 2921-2927. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12427756?

Nishimoto S., Kawane K., Watanabe-Fukunaga R., Fukuyama H., Ohsawa Y., Uchiyama Y., Hashida N., Ohguro N., Tano Y., Morimoto T., Fukuda Y. and Nagata S.

Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens

Nature 424, 1071-1074. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12944971?

Nagata S., Nagase H., Kawane K., Mukae N. and Fukuyama H.

Degradation of chromosomal DNA during apoptosis

Cell Death Differ. 10, 108-116. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12655299?

Nagase H., Fukuyama H., Tanaka M., Kawane K. and Nagata S.

Mutually regulated expression of caspase-activated DNase and its inhibitor for apoptotic DNA fragmentation

Cell Death Differ. 10, 142-143. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12655303?

Kawane K., Fukuyama H., Yoshida H., Nagase H., Ohsawa Y., Uchiyama Y., Okada K., Iida T., and Nagata S.

Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation

Nature Immunology 4, 138-144. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12524536?

Contin C., Pitard V., Itai T., Nagata S., Moreau J. F. and Dechanet-Merville J.

Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme - Implications for CD40 signaling

J. Biol. Chem. 278, 32801-32809. (2003).

http://www.ncbi.nlm.nih.gov/pubmed/12810728?