Biochemistry & Immunology,Immunology Frontier Research Center, Osaka University

■Curriculum Vitae

1968-72 Undergraduate Student Faculty of Science, University of Tokyo

1972-77 Graduate Student Department of Chemistry, Institute of
Medical Science, University of Tokyo

1977-77 Research Associate Department of Chemistry, Institute of Medical Science, University of Tokyo

1977-81　Post-Doctral Fellow Institute of Molecular Biology, University of Zurich

1982-87　Assistant Professor at the Institute of Medical Science,
University of Tokyo

1987-98　Head, Department of Molecular Biology, Osaka Bioscience Institute

1995-07　 Professor, Department of Genetics, Graduate School of Medicine, Osaka University

2002-07　 Professor, Integrated Biology Laboratories, Graduate School of Frontier Bioscience, Osaka University

2007-15　　Professor, Department of Medical Chemistry, Graduate School of Medicine, Kyoto University

2015-　　Professor, Immunology Frontier Research Center (IFRec), Osaka University

■Awards

1986 The Encouragement Award (Japan Biochemical Society)
1990 Erwin von Balz Preis (Tokyo)
1992 The Mochida Memorial Award (Tokyo)
1993 Nikkei BP Prize (Tokyo)
1994 Emil von Boehring Preis (Marburg Univ., Germany)
1995 Robert Koch Preis (Bonn, Germany)
1995 Osaka Science Prize (Osaka)
1996 Boehring-Kitasato Prize (Tokyo)
1997 Prix Lacassagne (Paris, France)
1997 Mellon Prize (Univ. of Pittsburgh, USA)
1998 Asahi Prize (Tokyo)
1998 Takmatsu Cancer Award (Tokyo)
1998 Uehara Prize (Tokyo)
2000 Japan Academy Prize, Imperial Prize (Japan)
2001 Person of Cultural Merits (Japan)
2011 Associate, The Japan Academy (Tokyo)
2012 Honorary Doctorate (Univ. of Zurich, Switzerland)
2012 Debrecen Award (Debrecen University/ Hungary)
2013 Keio Medical Science Prize (Keio Univ./Japan)
2015 Foreign Associate, The National Academy of Sciences
       (Washington DC, USA)
2017 The 2017 CDD Award (Dublin/Ireland)
2019 ECDO Honorary Prize 2019
2021 Fellow of the The American Association for Cancer Research
       (AACR)
2021 Pioneer, Australasian Cell Death Society

■Publications

Please see Google Scholar

■Editorial board

1994- Cell Death and Diff.
1995- Genes to Cell
1996- Apoptosis
1997- Int. Immunol.
1998- Immunity
1998- Exp. Cell Res.
1999- Biochem. Biophys. Acta
1999- IUBMB/Life
2000- Science
2000- Int. J. Cancer
2002- Cancer Cell

■Name

Takaharu Sakuragi
e-mail：tsakuragi [at] ifrec.osaka-u.ac.jp

■Education

2013 Faculty of Medicine, Kyoto University (M.D.)
2019 Graduate School of Medicine, Osaka University (Ph.D.)

■Research Experiences

04/2013-03/2015 Junior resident at Tenri Hospital (Nara)
04/2019-03/2021 Specially Appointed Researcher at Immunology Frontier Research Center, Osaka University
04/2021-present: Specially Appointed Assistant Professor at Immunology Frontier Research Center, Osaka University

■Awards

2016: Kibou Project Award from the Japanese Society for Immunology

■Publications

Watanabe, R., Sakuragi, T., Noji, H., and Nagata, S. (2018). Single-molecule analysis of phospholipid scrambling by TMEM16F.
Proc Natl Acad Sci U S A 115, 3066-3071.
https://doi.org/10.1073/pnas.1717956115

Sakuragi, T., Kosako, H., and Nagata, S. (2019). Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure.
Proc Natl Acad Sci U S A 116, 2907-2912.
https://doi.org/10.1073/pnas.1820499116

Nagata, S., Sakuragi, T., and Segawa, K. (2020). Flippase and scramblase for phosphatidylserine exposure.
Current opinion in immunology 62, 31 - 38.
https://doi.org/10.1016/j.coi.2019.11.009

Sakuragi, T., Kanai, R., Tsutsumi, A., Narita, H., Onishi, E., Nishino, K., Miyazaki, T., Baba, T., Kosako, H., Nakagawa, A., Kikkawa, M., Toyoshima, C., and Nagata, S.(2021)
The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nature Structural & Molecular Biology 28: 825-834
http://doi.org/10.1038/s41594-021-00665-8